Manager of in vivo Pharmacology or Senior Research Associate

125 - In-vivo Pharmacology · Emeryville, California
Department 125 - In-vivo Pharmacology
Employment Type Full-Time
Minimum Experience Manager/Supervisor

Caribou Biosciences, Inc. is a leading company in CRISPR genome engineering located in Berkeley, CA. Caribou's tools and technologies provide transformative capabilities to therapeutic development and the company is advancing an internal pipeline of gene-edited cell therapies for various oncology indications. The seven-year-old company has developed a best-in-class CRISPR genome engineering technology platform and has a leading intellectual property position. 

We are seeking a hands-on Manager of in vivo Pharmacology or Senior Research Associate to join our team at a site in the East Bay. The ideal candidate will interact closely with Scientists and Research Associates to drive discovery and development of new therapeutics. 

Responsibilities include:

  • Managing the facility and leading a team to conduct critical in vivo efficacy studies
  • Assuring compliance with protocols and SOPs; coordinating all interactions with IACUC for protocols, amendments, audits, and reporting
  • Training team members on required research procedures, including restraint, handling, surgery, anesthesia, injection (IV, IP, SC, and PO), and blood draw (RO bleed and cardiac puncture)
  • Designing, conducting, and interpreting preclinical efficacy studies
  • Developing and optimizing in vivo tumor models; performing and troubleshooting in vivo studies
  • Coordinating experiments with other Scientists and RAs across functional groups, collect, analyze, interpret, and report data, and stay current on relevant primary literature

Candidate must possess: 

  • Bachelor’s degree, Master’s degree or equivalent experience in Animal Science, Cell biology, Immunology, Biochemistry, Bioengineering
  • 8+ years of experience working in research operations, preferably in pharma or biotech
  • Strong scientific training and laboratory skills in immunology, immuno-oncology, and oncology
  • AALAS certification a plus
  • Experience managing, mentoring, and training others
  • Demonstrated proficiency with in vivo efficacy models
  • Hands-on experience with tumor cell inoculation, dosing via multiple routes, tissue collection, tumor measurements, and data recording
  • Experience with immune-compromised models and sterile handling techniques
  • Practical experience with cell culture, intravenous tail-vein injections, in vivo imaging techniques
  • Able to follow protocols and SOPs and execute multiple simultaneous tasks independently
  • Experience in managing, mentoring, and training others in all required research procedures
  • Demonstrated ability to work independently and as part of a small team, ability to manage internal and external resources and collaborations
  • Excellent verbal and written communication skills
  • Proven ability to work independently, as well as to collaborate with peers and work effectively in a fast-paced team-oriented environment
  • Strong organizational, time management, communication and interpersonal skills
  • Ability to work weekends as required

Caribou Biosciences, Inc. is a dynamic start-up company, and the successful candidate must have the ability and desire to work in a fast-paced environment.  For more information, please visit  Caribou is on Twitter.  Sign up to follow our Twitter feed @CaribouBio.

Caribou offers a comprehensive compensation package, as well as generous paid time off in addition to Company-observed holidays.  The Company provides medical, dental, and vision insurance, along with a 401(k) retirement savings plan which includes matching employer contributions. Caribou promotes a culture in which employees are respected and rewarded for hard work, innovation, personal initiative, and teamwork.

Caribou is an equal opportunity employer and does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Caribou prohibits the harassment of any individual on any of the basis listed above or any other characteristics protected under federal, state, or local laws.


Direct applicants only. No agencies please.

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  • Location
    Emeryville, California
  • Department
    125 - In-vivo Pharmacology
  • Employment Type
  • Minimum Experience